Ihe ọmụma
Minoxidil ntụ ntụ enwetala nlebara anya dị ukwuu na afọ ndị na-adịbeghị anya dị ka ihe ngwọta nwere ike ime maka ntutu isi. Nke a blọọgụ blọọgụ na-abanye n'ime nrụpụta nke minoxidil ntụ ntụ na-akwalite uto ntutu, na-aza ajụjụ ndị a na-ajụkarị, na inye nghọta dabere na nyocha ugbu a na ahụmịhe onye ọrụ.
Kedu ka Minoxidil Powder si arụ ọrụ iji kwalite uto ntutu?
Minoxidil ntụ ntụ, ụdị kristal nke ihe na-arụ ọrụ nke a na-ahụ na ọgwụgwọ ntutu isi na-ewu ewu, na-arụ ọrụ site n'ọtụtụ usoro iji kwalite uto ntutu. Mgbe etinyere ya n'isi, ọ na-eme mgbanwe mgbanwe nke na-enye ya ohere ịbanye n'ime akpụkpọ ahụ wee rute ntutu isi.
Otu n'ime ụzọ ndị mbụ minoxidil ntụ ntụ na-akwalite uto ntutu bụ site n'ịbawanye ọbara eruba n'isi. Mgbasa mgbasawanye a na-ebuga oxygen na nri ndị na-edozi ahụ na ntutu isi, na-emepụta ebe kachasị mma maka uto ntutu. Mmụba ọbara na-eruba na-enyekwa aka ịgbasa na ịgbalite ntutu isi ndị gbajiri agbaji, nwere ike gbanwee usoro mbelata nke a na-ahụkarị na isi nkwọcha nwoke na nwanyị.
Ọzọkwa, a kwenyere na ntụ ntụ minoxidil na-agbatị oge anagen (eto eto) nke usoro ntutu isi. Site n'ịgbatị oge a, ọ na-enye ohere ka ntutu na-eto ogologo oge tupu ọ daa mbà n'obi, na-eme ka ntutu dị ogologo ma na-adịwanye mma ka oge na-aga. Nnyocha ụfọdụ na-egosi na minoxidil nwekwara ike ịbawanye nha nke ntutu isi, na-eduga n'ịmepụta eriri ntutu siri ike na nke siri ike karị.
Akụkụ ọzọ dị mkpa nke minoxidil ntụ ntụ na-eme bụ ikike imeziwanye ihe ụfọdụ na-eto eto na prostaglandins n'isi. Ngwakọta ndị a na-ekere òkè dị mkpa na uto ntutu na ịgba ígwè. Dịka ọmụmaatụ, egosipụtara na minoxidil na-amụba okwu nke vaskụla endothelial growth factor (VEGF), nke na-akwalite nhazi nke arịa ọbara ọhụrụ n'isi, na-eme ka nri na-edozi ahụ na-aga n'ihu na ntutu isi.
Ọ dị mkpa iburu n'obi na mgbe minoxidil ntụ ntụ nwere ike ịdị irè maka ọtụtụ ndị mmadụ, nsonaazụ nwere ike ịdị iche. Ihe ndị dị ka ihe na-akpata isi na-akpata ntutu isi, ọkwa nke ntutu isi na-aga n'ihu, na nzaghachi onye ọ bụla na ọgwụgwọ ahụ nwere ike imetụta irè ya. Ojiji na-agbanwe agbanwe na ogologo oge dị mkpa iji hụ na jikwaa nsonaazụ.
Enwere ike iji ntụ ntụ Minoxidil maka uto ajị agba?
Iji minoxidil ntụ ntụ maka uto ajị agba enwetawo ewu ewu n'afọ ndị na-adịbeghị anya, n'agbanyeghị na akwadoghị ya maka nzube a site n'aka ndị na-achịkwa dịka FDA. Ọ bụ ezie na a na-erekarị minoxidil ma mụọ maka uto ntutu isi, ọtụtụ ụmụ nwoke anwalela iji ya mee ntutu ihu na ọkwa dị iche iche nke ịga nke ọma.
Sayensị n'azụ iji minoxidil ntụ ntụ maka ito ajị agba dabere n'otu ụkpụrụ ahụ dị ka iji ntutu isi. Ihe na-arụsi ọrụ ike na-arụ ọrụ site n'ịbawanye ọbara na-eruba na ntutu isi, nwere ike ịkpali ha ime ka ntutu dị ogologo na nke zuru oke. N'ihe banyere uto afụ ọnụ, tiori bụ na minoxidil nwere ike ịgbalite follicles dormant ma ọ bụ welie uto nke ntutu ihu dị adị.
Ọtụtụ ihe na-eme ka mmasị na-arị elu nke iji minoxidil ntụ ntụ maka nkwalite afụ ọnụ:
1. Ihe akaebe nke anecdotal: Ọtụtụ ndị ọrụ akọpụtala nsonaazụ dị mma, na-ekerịta ahụmịhe ha na mgbasa ozi ọha na eze na forums. Akaụntụ akụkọ ihe mere eme ndị a, nke na-esokarị foto tupu na mgbe emechara, akwalitela mmasị na iji akara ngosi a.
2. Mfe nke ngwa: Ụdị ntụ ntụ nke minoxidil nwere ike ịgwakọta ngwa ngwa ma tinye ya na mpaghara ihu, na-enye ohere maka ọgwụgwọ ezubere iche nke patchy ma ọ bụ ebe dị mkpa nke ajị agba.
3. Enwere ike ịhazi ya: Ndị ọrụ nwere ike ịhazigharị ntinye nke ngwọta minoxidil, nwere ike inye ohere maka ụzọ ahaziri ahazi maka mkpali uto afụ ọnụ.
4. Ịnweta: Dị ka ngwaahịa na-ere ahịa, minoxidil ntụ ntụ dị mfe ịnweta ma e jiri ya tụnyere ọgwụgwọ ndenye ọgwụ maka uto ntutu.
Otú ọ dị, ọ dị mkpa ịtụle ọtụtụ isi ihe mgbe ị na-eche echiche iji minoxidil ntụ ntụ maka uto ajị agba:
1. Nchọpụta sayensị na-amachi oke: Ọ bụ ezie na enwere ọtụtụ ọmụmụ banyere minoxidil maka uto ntutu isi, nyocha lekwasịrị anya kpọmkwem na nrụpụta ya maka uto ajị agba nwere oke. Ọtụtụ ihe akaebe maka ịdị irè ya na mpaghara a bụ akụkọ ifo.
2. Mgbanwe nke onye ọ bụla: Dị ka ọ dị na ọgwụgwọ uto ntutu ọ bụla, nsonaazụ nwere ike ịdịgasị iche site na onye gaa na onye. Ihe ndị dị ka mkpụrụ ndụ ihe nketa, afọ, na ahụike zuru oke nwere ike imetụta ịdị irè nke minoxidil maka uto ajị agba.
3. Nkwekọrịta bụ isi: Ndị na-akọ ihe ịga nke ọma na minoxidil maka uto afụ ọnụ na-ekwukarị mkpa ọ dị na-agbanwe agbanwe, iji ogologo oge mee ihe. Ọ nwere ike were ọtụtụ ọnwa nke ngwa mgbe niile ka ịhụ nsonaazụ pụtara.
4. Mmetụta nwere ike ime: Ọ bụ ezie na a na-echekarị na ọ dị mma, minoxidil nwere ike ịkpata mmetụta ndị dị ka mgbakasị anụ ahụ, nkụchi, ma ọ bụ ntutu isi na-achọghị na mpaghara ndị dị n'akụkụ. Ekwesịrị iji nlezianya tụlee ihe ize ndụ ndị a, karịsịa mgbe ị na-etinye ngwaahịa ahụ na akpụkpọ ihu dị nro.
5. Mmetụta nkwụsị: Ọ bụrụ na a kwụsịrị iji minoxidil mee ihe, uru ọ bụla na uto ajị agba nwere ike ịla n'iyi ka oge na-aga, n'ihi na ngwaahịa ahụ anaghị agbanwe ntutu isi kpamkpam.
6. Ndụmọdụ na-atụ aro: Tupu iji minoxidil ntụ ntụ maka uto ajị agba, ọ bụ ihe amamihe dị na ya ịkpọtụrụ onye ọkachamara ahụike ma ọ bụ onye na-ahụ maka anụ ahụ, karịsịa maka ndị mmadụ nwere ọnọdụ akpụkpọ anụ mbụ ma ọ bụ ndị na-aṅụ ọgwụ ndị ọzọ.
Ọ bụ ezie na iji minoxidil ntụ ntụ maka uto ajị agba na-anọgide na-enwe mmasị na nnwale, ọ dị mkpa ịbịakwute ya na atụmanya ziri ezi na nghọta doro anya nke ihe ize ndụ na njedebe ndị nwere ike ime. Ka nyocha na mpaghara a na-aga n'ihu na-etolite, anyị nwere ike nweta nghọta doro anya banyere nrụpụta ọrụ na ogologo oge nke iji minoxidil maka nkwalite ntutu ihu.
N'ikpeazụ, mgbe minoxidil ntụ ntụ na-egosi nkwa n'ịkwalite uto ntutu, gụnyere enwere ike ịkwalite afụ ọnụ, ịdị irè ya nwere ike ịdị iche n'etiti ndị mmadụ n'otu n'otu. Dị ka ọ dị na ọgwụgwọ uto ntutu ọ bụla, ịdịgidesi ike, ndidi, na atụmanya ziri ezi bụ isi. Gwa onye ọkachamara ahụike oge niile tupu ịmalite usoro uto ntutu ọhụrụ ọ bụla iji hụ na ọ dabara maka mkpa gị na akụkọ ahụike gị.
Ọ bụrụ na ị nwekwara mmasị na ngwaahịa a ma chọọ ịmatakwu nkọwa ngwaahịa, ma ọ bụ chọọ ịmata maka ngwaahịa ndị ọzọ metụtara, biko nweere onwe gị ịkpọtụrụ. iceyqiang@aliyun.com.
References
1. Suchonwanit, P., Thammarucha, S., & Leerunyakul, K. (2019). Minoxidil na ojiji ya na nsogbu ntutu: nyocha. Nhazi ọgwụ, mmepe na ọgwụgwọ, 13, 2777-2786.
2. Badri, T., Nessel, TA, & Kumar, DD (2021). Minoxidil. Na StatPearls. Mbipụta StatPearls.
3. Messenger, AG, & Rundegren, J. (2004). Minoxidil: usoro nke ime ihe na uto ntutu. Akwụkwọ akụkọ Britain nke Dermatology, 150 (2), 186-194.
4. Rossi, A., Cantisani, C., Melis, L., Iorio, A., Scali, E., & Calvieri, S. (2012). Minoxidil eji na dermatology, mmetụta na-adịbeghị anya patents. Ikike n'oge na-adịbeghị anya na nchọpụta ọgwụ ọjọọ na ọzịza, 6(2), 130-136.
5. Olsen, EA, Dunlap, FE, Funicella, T., Koperski, JA, Swinehart, JM, Tschen, EH, & Trancik, RJ (2002). Nnwale ụlọ ọgwụ na-enweghị usoro nke 5% topal minoxidil vesos 2% minoxidil topal na placebo na ọgwụgwọ androgenetic alopecia na ụmụ nwoke. Akwụkwọ akụkọ nke American Academy of Dermatology, 47(3), 377-385.
6. Blume-Peytavi, U., Hillmann, K., Dietz, E., Canfield, D., & Garcia Bartels, N. (2011). Nnwale kpuru ìsì nke 5% minoxidil foam otu ugboro kwa ụbọchị karịa 2% minoxidil ngwọta ugboro abụọ kwa ụbọchị na ọgwụgwọ androgenetic alopecia na ụmụ nwanyị. Akwụkwọ akụkọ nke American Academy of Dermatology, 65 (6), 1126-1134.e2.
7. Gupta, AK, & Charrette, A. (2015). Minoxidil Topical: Nyocha usoro na Meta-Analysis nke arụmọrụ ya na Androgenetic Alopecia. Akpụkpọ anụ, 13 (3), 185-189.
8. Prager, N., Bickett, K., French, N., & Marcovici, G. (2002). Nnwale a na-achịkwaghị achịkwa, nke kpuru ìsì abụọ, ebe a na-achịkwa ebebo iji chọpụta ịdị irè nke ndị na-egbochi botanical nke 5-alpha-reductase na ọgwụgwọ androgenetic alopecia. Akwụkwọ akụkọ nke ọgwụ ọzọ na mgbakwunye, 8(2), 143-152.
9. Kanti, V., Messenger, A., Dobos, G., Reygagne, P., Finner, A., Blumeyer, A., Trakatelli, M., Tosti, A., Del Marmol, V., Piraccini, BM, Nast, A., & Blume-Peytavi, U. (2018). Ntuziaka dabere na ihe akaebe (S3) maka ọgwụgwọ androgenetic alopecia na ụmụ nwanyị na ụmụ nwoke - ụdị dị mkpụmkpụ. Akwụkwọ akụkọ nke European Academy of Dermatology and Venereology, 32(1), 11-22.
10. Lee, SW, Juhasz, M., Mobasher, P., Ekelem, C., & Mesinkovska, NA (2018). Nyochaa usoro nke Topical Finasteride na ọgwụgwọ Androgenetic alopecia na ụmụ nwoke na ụmụ nwanyị. Akwụkwọ akụkọ banyere ọgwụ ọjọọ na Dermatology, 17 (4), 457-463.
